polyubiquitinatedproteins

由 HP Hemantha 著作 · 2014 · 被引用 110 次 — Polyubiquitination produces molecular signals that depend on which of the seven lysines in Ub (K63, K48, K33, K29, K27, K11, K6) is used for ...

2024年3月21日 — Herein we show that UBQLN2 phase separation is modulated by polyubiquitinated substrates in a linkage-dependent fashion. Further, we show that ...

由 D Morimoto 著作 · 2015 · 被引用 89 次 — Ubiquitin is known to be one of the most soluble and stably folded intracellular proteins, but it is often found in inclusion bodies ...

由 GL Grice 著作 · 2016 · 被引用 334 次 — Lysine-48 (K48) linked polyubiquitin chains are well established as the canonical signal for proteasomal degradation, but recent studies show a ...

由 W Li 著作 · 2008 · 被引用 417 次 — Ubiquitin and its kin (Ubiquitin-like proteins, or Ubls) are a family of highly conserved proteins that share similarity, not only in structure, but also in the ...

This protocol describes in detail how to determine if your protein of interest is poly-ubiquitinated or multi-mono-ubiquitinated and why this distinction is ...

Polyubiquitin chains serve as recognition signals for the proteasome, the major regulator of protein abundance in cells, often initiating proteolysis of ...

Ubiquitinated protein aggregates are hallmarks of a range of human diseases, including neurodegenerative, liver, and muscle disorders. From: Autophagy: Cancer, ...